Pedia cramps Description for Physicians

Medicinal plants can be used to treat many diseases, especially digestive problems, due to their various effective ingredients. Their effective material can have their own application without affecting or interfering with each other. The compounds in this medicine, due to the effect of damaging on intestinal detoxification bacteria, reduce the bloating, swelling and crampsing. These compounds are also effective in colon spasm.

Pedia-cramps herbal distilled is a combination of 10 different medicinal plants: Thymus vulgaris, Platanus orientalis, Salix alba, Mentha polegium, Malva sylvestris, Trachyspermum copticum, Hyssopus officinalis, Echium amoenum, Ziziphus zizyphus and Mentha piperita. All of them have therapeutic properties to treat digestive problem in children and infants. Pedia-cramps has been produced by Parsiteb Company.

Each ml of Pedia-cramp contains Menthol, Pinocamphone, Thymol, Salicin, Anthocyanin, Anethole, 1,8-Cineole and Phytol (It should be noted that this component is an essential component of these plant that is effective in the treatment of digestive diseases in children and infants).

Other usages of this herbal distilled are following:
Boosting children’s digestive system, treating bloating, indigestion treatment, anti-nausea, treating excess gastric acid, treating gastric acid reflux, pain relievers, protecting the gastric mucosa.

The early stages of the clinical tests were conducted in a pilot experiment. For this purpose the product was used as a supplement in the diet of patients. So, repeatedly checked the positive effects of the product on children and infants with digestive problems. The results have shown that in 80% of the people who were considered as clinical community, taking this diet disrupted the symptoms of the disease. The minimum performance of this product for other people has been to prevent the progression of digestive disease in children and infants.

The application of this product is:

Infants: Maximum 2 times per day (every time 2 ml)
Children: Maximum 2 times per day (every time 5 ml)

Pharmacological effects of Pedia-cramps (10 medicinal plants)

Preventing reflux

One of the most common diseases in infants is acid reflux and digestive colic. Acid reflux is also known as heartburn. Acid reflux creates a burning pain in the chest area, often after eating.

Recently, this disease is common in children and infants and parents are often use chemical medicines, but one of the most useful product is the use of Pedia-Cramps as an herbal treatment.

It is also common in adults and cause other diseases such as chest pain, asthma, laryngitis, even tooth decay, sinusitis, esophageal stricture, intestinal metaplasia and adenocarcinoma of esophagus.

The compounds in this product increase gastrointestinal uptake by improving the upper gastrointestinal tract, restoring food to the esophagus (reflux) and treating indigestion.

This product releases acetylcholine from the cholinergic nerves in the gastrointestinal system. Also, the compounds used in the product reduce gastric acidity, improve reflux symptoms and treat the esophagus. Therefore, according to the articles, Pedia-Cramps has a good potential to reduce gastric acid and pepsin secretion that play the key role in the esophagus damage.

Against Bloating

Bloating is one of the most common disorders of the digestive system. The accumulation of gasses due to bloating causes many problems. Bloating in most cases is considered as a functional disease.

The peppermint in this product relaxes the esophagus. Therefore, it has anti-inflammatory effect and treat digestive problems. The compounds of this product, due to the effect of damaging on intestinal detoxification bacteria, reduce the bloating, swelling and cramping.

These compounds are also effective in colon spasm. Medicinal plants in Pedia-Cramps can be used to treat gastro-intestinal diseases due to the presence of various active substances without affecting or interfering with their active ingredients. Therefore, controlling digestive complications, including bloating, will have beneficial effects for mothers and infants.

The active components of Pedia-Cramps can eliminate the symptoms of bloating by creating a complete digestion. Menthol in mint probably causes calcium antagonistic effects due to relaxation of the smooth muscle of the colon wall.

Pain Reliever

The extract of thyme leaves used in this product, with the blockage of calcium channels, reduces the ion entry and then reduces the contraction caused by chloroceptin in digestive system. Menthol in the product inhibits pain through the activity of kappa-opioid receptors and signal transduction. Also, Peppermint extract reduces pain by reducing the acid secretion of the stomach.

Protecting the gastric mucosa

Increasing the secretion of gastric acid is the main cause of gastric mucosal damage. There is a direct relationship between the level of gastric acid secretion and peptic ulcer disease. Peppermint extract affects the nervous system by relaxing muscle and even vascular contraction. So it can be effective in seizure corrosion.

Reduce the secretion of gastric acid

Partial cells have multiple receptors for stimulating and inhibiting the secretion of gastric acid. The binding of effective factors in the secretion of gastric acid to its receptors leads to change in intracellular processes. After binding to the histamine 2 receptor (H2) on the surface of the parietal cells, Histamine can increase the level of intracellular cAMP, it leads to active a batch of protein kinases that phosphorylate intermediate proteins and ultimately increase the level of gastric acid secretion.


The compounds present in this product through post-synaptic obstruction of dopamine receptors in the CNS has an antiemetic effect. Pedia-Cramps increases the ability of the esophageal sphincter rest and cause the pyloric sphincter to relax. The compounds in the Pedia-Cramps reduce stomach contractions, but it increase the activity of the gastro-intestinal system. Also, the compounds in this product have anti-serotonin effects. It have inhibitory effects against free radicals that affect vomiting.

Oxidative stress plays an important role in nausea. Accordingly, it can be attributed some of the anti-nausea effects of this product to the presence of antioxidant compounds used in Pedia-Cramps.

Through inhibition of cyclooxygenase and lipoxygenase pathways, which prevent the metabolism of Arachidonic Acid. Therefore, the anti-inflammatory effects of Pedia-Cramps can be controlled by inhibiting the production of prostaglandins and leukotrienes.

Diarrhea treatment

Diarrhea is one of the most important health problems especially in children around the world and is one of the most common causes of child mortality. In Iran, diarrhea is the second leading cause of death in children after respiratory infections. The most common causes of infectious diarrhea in children are viral and bacterial causes. Many studies have proved their anti-diarrhea effects on the biological activity of some plant extracts. Medicinal plants used in Pedia-Cramps, including Thymus vulgaris, have anti-contractile properties, delay the movements of the intestine and reduce their secretions and have anti-diarrheal properties. The antimicrobial properties of other medicinal plants in Pedia-Cramps prevent the growth of pathogens in the digestive systems.


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